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Hemofilia? Penyebab, Penetalaksanaan, dan komplikasi

A.     Definisi Hemofilia. Hemofilia adalah gangguan pendarahan konginetal gen X yang disebabkan oleh defisiensi faktor koagulasi VIII (Hemofilia A) atau Faktor IX (Hemofilia B). Defisiensi ini adalah hasil mutasi gen faktor pembekuan darah (Srivastava et al, 2012). Hemofilia biasanya menyebabkan sulitnya darah koagulasi sehingga menyebabkan pendarahan spontan pada otot, sendi, atau organ internal. Diperlukan terapi preventif untuk mencegah pendarahan berulang dengan faktor koagulasi (Bauer, 2015). B.      Etiologi. Hemofilia mempengaruhi Laki-laki dari gen carrier ibu. Gen Faktor VIII dan gen Faktor IX rentan terhadap mutasi, dan sebanyak 1/3 dari semua kasus adalah hasil mutasi spontan dimana sebelumnya tidak ada riwayat keluarga (Srivastava et al, 2012). C.      Epidemiologi. Hemofilia diperkirakan terjadi pada 1 banding 10.000 kelahiran. Estimasi ini berdasarkan survey global tahunan, bahwa pasien Hemofilia sekitar 400.000 pasien. Hemofilia A terdapat 80-85% dari t
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Blaming and Accusing Someone

Pernahkah kalian menyalahkan seseorang? Apa yang menyebabkan kalian menyalahkan seseorang? Kita bisa menyalahkan seseorang saat mereka melakukan kesalahan yang merugikan kita ataupun merugikan orang lain. Untuk itu, kalian bisa gunakan expresi di bawah ini: Blaming someone Blaming is an expression that is used to say on somebody the responsibility for something done (badly or wrongly) or not done: He blamed his teacher for his failure . Expressing Blaming expression It was your fault ! You are the one to blame .... Serves you right You are to blame for  steel my …
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Admitting Mistakes and Making Promises

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      Admitting Mistake is the way you to admit and ask for a sorry of your mistake. Benefits of Admitting   Mistakes:       It demonstrates your courage       It demonstrates your humanity       It engenders more trusting relationships       It creates greater organisational value
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Conditional Sentence

Conditional sentence is used for expressing our hope or expectation toward something. A conditinal sentence consist of two part : “main clause” and “if clause”. There are four types of conditional sentences in english: •          1st conditional sentences •        2nd conditional sentences •        3rd conditional   sentences •        Conditional Sentence without “IF” (Inversion)
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Making Suggestion and Requesting Something

Making Suggestion is how you express your suggestion to someone .   There are a number of ways used when making suggestions : 1)            WHAT ABOUT/HOW ABOUT ... + Base form + -ING •        What about going to the swimming pool tomorrow? •        How about going to the swimming pool tomorrow? 2)            WHY + Negative •        Why don't we go to the swimming pool tomorrow? 3)            IMPERATIVE: Let's + Base form •        Let's go to the swimming pool tomorrow!  4)            COULD •        We could go to the swimming pool tomorrow. 5)             DO YOU WANT + the infinitive •        Do you want to go to the swimming pool tomorrow?
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Complaining and Giving Instruction

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Complaining Complaints are expressions of "displeasure or annoyance" in response to an action that is seen by the speaker as unfavorable. Making a complaint:       I do wish you could….       Excuse me, I’m afraid…       I wish you wouldn’t mind…       Would you mind (doing)….?       Well, it is good for you to….       (Honestly!) I’m fed up with …       I wonder if you could help me…..       I’m sorry to have to say this, but….       Look, I’m sorry to trouble you, but….       (Well,) this is the most unsatisfactory.       Wouldn’t it be a good idea to/ not to….       I’ve got a bit of a problem here, you see……       Excuse me, there appears to be something wrong…       Excuse me, there seems to be something wrong with…
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Explanation Text

explanation text is explaining how something forms or why the thing happens. So when we read an explanation text, the text will cover the answer of "how" or "why" relating to a thing or a phenomenon. An explanation text is organized with the generic structure of a general statement and a sequence of explanations. If you need to know the basic definition of explanation texts. Generic structure of Explanation General statement ; stating the phenomenon issues which are to be explained. Sequenced explanation ; stating a series of steps which explain the phenomena. Language Feature of Explanation Featuring generic participant; sun, rain, etc Using chronological connection; to begin with, next, etc Using passive voice pattern Using simple present tense How Day and Night Happen The sun seems to rise in the morning, crosses the sky during the day and sets at night. However the sun does not actually move around the earth. Earth's turning on its
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